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  1. Effects of Sweeteners on the Gut Microbiota: A Review of …

    Although nonnutritive sweeteners (NNSs) are considered safe and well tolerated, their effects on glucose intolerance, the activation of sweet taste receptors, and alterations to the composition of the …

  2. How Artificial Sweeteners Disrupt the Gut Microbiome, Or Do They?

    Mar 31, 2025 · Some studies indicate that regular consumption of artificial sweeteners may disrupt gut microbiota, altering the balance of beneficial bacteria.

  3. Effect of low-and non-calorie sweeteners on the gut microbiota: A ...

    Jan 1, 2024 · Use of non-nutritive sweeteners (NNSs) has increased worldwide in recent decades. However, evidence from preclinical studies shows that sweetener consumption may induce glucose …

  4. What Soda Is Better for You? Ranking the Options

    Jan 14, 2026 · Research has focused on the effect of non-nutritive sweeteners on the gut microbiome. Studies suggest that certain sweeteners, like saccharin and sucralose, can alter the composition and …

  5. How Artificial Sweeteners Affect Gut Bacteria And Digestion

    Aug 1, 2025 · Recent research suggests these sugar substitutes may alter your gut microbiome, affecting digestion and potentially contributing to issues like bloating, glucose intolerance, or even …

  6. The Truth About Artificial Sweeteners and Gut Bacteria Health

    Mar 31, 2025 · Discover how artificial sweeteners affect gut bacteria health. Learn about their potential risks, benefits and how they impact your microbiome and digestion.

  7. Artificial Sweeteners And Gut Bacteria: What’s The Story? - ZOE

    Nov 12, 2025 · Each sweetener had measurable and distinct effects on the gut and oral microbiome. The scientists also showed that saccharin and sucralose negatively affected participants’ blood sugar …

  8. Are Sugar-Free Drinks Like Diet Coke a Healthier Choice?

    Do diet sodas affect gut health? Emerging research suggests that artificial sweeteners may disrupt the gut microbiome—the trillions of bacteria that help regulate digestion, inflammation, and immune …

  9. Sweeteners 101: How Sugar Alternatives Affect Your Gut

    Feb 3, 2025 · Learn how sweeteners affect your gut microbiome and explore research-backed tips to make choices that support your gut health.

  10. Does Healthy Diet Soda Exists?

    2 days ago · The artificial sweeteners commonly found in diet sodas, like aspartame and sucralose, may cause spikes in blood sugar and insulin levels, raising further health concerns.

  11. We Asked a Doctor If Diet Soda Is Healthier Than Alcohol

    4 days ago · Diet soda is fine to drink in moderation—and it's definitely better than alcohol—but don't replace your water with diet soda. There's also some debate about how diet sodas, specifically their …

  12. Artificial Sweeteners Compared: Aspartame vs Sucralose vs Stevia vs ...

    May 19, 2025 · Artificial sweeteners like aspartame and sucralose, despite being calorie-free, may alter metabolic responses and gut microbiota. Disruptions in the gut microbiome have implications for …

  13. Are Artificial Sweeteners Bad for Gut Health? - MSN

    Even though more long-term human studies are still needed, the pattern is clear: artificial sweeteners can negatively affect the gut, especially if your microbiome is already compromised.

  14. Do no-calorie artificial sweeteners have any effect on gut health or ...

    Aug 19, 2022 · New research finds that no-calorie artificial sweeteners such as aspartame, saccharin, stevia, and sucralose affect gut health and can alter glycemic responses.

  15. Artificial Sweeteners and Gut Health: What’s the Connection?

    Jul 26, 2025 · While direct causation is still being investigated, some evidence points to artificial sweeteners contributing to or exacerbating gut inflammation, either directly or indirectly by altering …

  16. RESEARCH ALERT: Artificial Sweeteners Significantly Alter the Small ...

    Sucralose, aspartame, saccharin and the plant-based stevia leaf extract are among the most popular. These artificial sweeteners are frequently used by people trying to reduce their sugar intake or lower …

  17. Artificially Sweetened Beverages: Up-to-date scientific evidence.

    Sep 12, 2023 · Artificially sweetened beverages (ASBs), most commonly diet sodas, are drinks that use nonnutritive sweeteners (NNS) like aspartame, sucralose, or acesulfame K instead of sugar.

  18. Some Sugar Substitutes Affect Blood Glucose and Gut Bacteria

    In an August 2022 study, participants who consumed sugar substitutes showed an altered microbiome and spikes in blood glucose

  19. Impact of artificial sweeteners and rare sugars on the gut microbiome

    Recently, consumption of these sweeteners in diet foods and beverages has increased dramatically, raising concerns about their health effects. This review examines the types and characteristics of …

  20. Low-calorie sugar alternatives could negatively affect gut health ...

    Aug 22, 2022 · All four substances tested in the study – saccharin, sucralose, aspartame and stevia – were found to change the gut microbiome, the collection of microbes in the gut that help protect …

  21. Three sweetened drinks a day has 'minimal effect' on gut microbiome ...

    Nov 6, 2020 · High consumption of sweeteners such as aspartame or sucralose over a two week period has minimal effect on gut microbiota composition or SCFA production, according to the secondary …

  22. Dietary Guidance, Sensory, Health and Safety Considerations When ...

    Feb 25, 2025 · The Effects of Non-Nutritive Artificial Sweeteners, Aspartame and Sucralose, on the Gut Microbiome in Healthy Adults: Secondary Outcomes of a Randomized Double-Blinded Crossover …

  23. How Does Diet Soda Affect Blood Sugar? - Biology Insights

    Artificial sweeteners like sucralose, aspartame, stevia, and acesulfame potassium are not carbohydrates and do not contain glucose. Since they are non-caloric and cannot be broken down into simple …

  24. Artificial Sweeteners May Change Our Gut Bacteria in Dangerous Ways

    Apr 1, 2015 · The Israeli study suggests that artificial sweeteners enhance the populations of gut bacteria that are more efficient at pulling energy from our food and turning that energy into fat.

  25. Exploring the Long-Term Effect of Artificial Sweeteners on Metabolic Health

    The findings are consistent with current research suggesting that ASs like saccharin, sucralose, and aspartame can disrupt the gut microbial balance, potentially leading to metabolic disturbances.

  26. Do artificial sweeteners trigger migraines and blood sugar imbalance?

    Artificial sweeteners like aspartame and sucralose are widely used in diet sodas, sugar-free desserts, and packaged foods. While they help reduce calorie intake, some individuals report headaches ...

  27. What Happens to Your Heart and Brain When You Consume ... - Health

    5 days ago · Artificial sweeteners, like aspartame and xylitol, offer sweetness without the calories of sugar. But are they actually healthy for your heart and brain?