A capitalized "miR-" refers to the mature form of the miRNA, while the uncapitalized "mir-" refers to the pre-miRNA and the pri-miRNA. [41] The genes encoding miRNAs are also named using the same …

Dec 17, 2025 · A microRNA (miRNA) is a small molecule in cells, typically about 21–25 nucleotides in length, that plays a crucial role in the regulation of gene expression.

In this review, we provide an update on canonical and non-canonical miRNA biogenesis pathways and various mechanisms underlying miRNA-mediated gene regulations. We also summarize the current …

Jun 28, 2023 · Here, we summarize the current understanding of miRNA biogenesis, function and regulation, and outline challenges to address in the future.

Jun 1, 2025 · A thorough understanding of miRNA biosynthesis and the distinct pathways involved in both animal and plant cells is of paramount importance for fully elucidating the regulatory networks …

The journey of a microRNA begins in the cell’s nucleus, where miRNA genes are transcribed by RNA polymerase II into a long primary miRNA (pri-miRNA) transcript.

Dive into the world of microRNA (miRNA). Learn how these master regulators fine-tune gene expression and their crucial role in cancer, metabolic, and neurodegenerative diseases.

They have been linked to many diseases, and currently miRNA-mediated clinical trial has shown promising results for treatment of cancer and viral infection. This review provides an overview and …

Explore how microRNA (miRNA) regulates gene expression and functions and holds potential for treating diseases like cancer and autoimmune disorders.

Although the first miRNA was identified over ten years ago, it is only recently that researchers have begun to understand the scope and diversity of these regulatory molecules.