Rapid changes in mitochondrial DNA allele frequency between generations have been explained by an 'mtDNA bottleneck' in the germ line, and it has recently been proposed that mtDNA aggregates, or ...

Because mtDNA is only passed down along maternal lines and mutates at predictable rates, it has been used to help trace migration routes of early humans. In this activity, students will learn how ...

Management of mitochondrial-related heart disease relies on multidisciplinary care and symptom control, as targeted gene-editing therapies are limited.

Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...

Mitochondria contain their own genome, which is maternally inherited and codes for polypeptides forming the mitochondrial respiratory chain. Mitochondrial DNA (mtDNA) has a structure and code ...

When it comes to identification with DNA, forensic scientists have two basic approaches at their disposal. One approach analyzes nuclear DNA and is useful in identifying someone who is alive or has ...

On December 15, 2016, the Human Fertilisation and Embryology Authority in the United Kingdom approved the use — in certain, specific cases — of a technique that is based on in vitro fertilization (IVF ...