To cause tuberculosis, the bacterium Mycobacterium tuberculosis must obtain nutrients from host cells. This is facilitated at least in part by protein complexes known as transporters. The structure of ...

Besides their normal role, pump overexpression confers drug resistance. Knowing the structure is a step to disabling the pumps with inhibitors BIRMINGHAM, Ala. – Tuberculosis is the world’s leading ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

To support drug discovery, a new study has revealed fundamental features of the transcription cycle in the bacteria that causes tuberculosis.

AMES, Iowa – Edward Yu took note of the facts – nearly 2 million deaths each year, 9 million infected each year, developments of multidrug-resistant, extensively drug-resistant and now totally ...

Tuberculosis, caused by the bacterium Mycobacterium tuberculosis (Mtb) kills upwards of 1.6 million people a year, making it one of the leading causes of death by an infectious agent worldwide -- and ...