The RNA-activated protein kinase PKR inhibits translation initiation by sensing long viral double-stranded RNA. A new report indicates that PKR is also activated by a cellular mRNA, but only when ...
Ribosomes—the tiny factories that build proteins in our cells—don't all work with the same efficiency. Researchers from Japan ...
Figure 1: PDF specifically binds to the 50S ribosomal subunit via its C-terminal helix. On the basis of our biochemical results, we designed crystallographic experiments. We reasoned that structural ...
Why is ribosome display used? Ribosome display can be used to study the protein-protein interactions that occur during everyday metabolism. In addition, the technique allows scientists to identify the ...
HHMI scientists and their colleagues discover a new mechanism of protein synthesis. Ribosomes are the cell’s molecular machines, responsible for translating genetic information in messenger RNA into ...
The Times of Israel on MSN
Israeli scientists say tiny organisms can revamp their own RNA to survive extreme heat
Using a novel method, Weizmann Institute of Science researchers map 16 types of simultaneous changes in dozens of samples; ...
Researchers have artificially engineered a complete ribosome—the cell-based machine that translates mRNA into proteins—in the laboratory. The ability to engineer the ribosome not only could help ...
Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...
Scientists have found that human ribosomes decode mRNA slower than bacteria, with implications for drug development. Scientists at St. Jude Children's Research Hospital revealed that human ribosomes ...
DNA gets all the glory, but genetic material wouldn’t be anywhere without ribosomes — cellular protein factories that build everything from insulin to fingernails. The Royal Swedish Academy of ...
Over the past decade or so, nanotechnology has produced small-molecule machines that can walk, perform basic chemical reactions, or do mechanical tricks, such as spin around or ratchet. Yet the field ...
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