Retroviruses have colonized vertebrate hosts for millions of years by inserting their genes into host genomes, enabling their inheritance through generations as endogenous retroviruses (ERVs).
In the adult mammalian brain, new neurons are generated and incorporated into the existing neural circuits in restricted regions including the dentate gyrus and the olfactory bulb 1. Although studies ...
In principle, transient nongenetic modification of a noninfectious gene transfer virus enabling a one time infection and transduction of human cells could eliminate the risk of formation of ...
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