In the relaxation of the smooth muscle, PGE1 works mainly via the prostaglandin E2 receptor (EP receptors). After combining to EP receptor, PGE1 acts by increasing the synthesis of cyclic-adenosine ...

Prostaglandin E 2 (PGE 2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes through four G protein-coupled receptor (GPCR) subtypes: EP1–EP4. While ...

Prostaglandin E2 (PGE2) responses could play a role in Alzheimer disease (AD) pathology. That’s the conclusion of a study reported in the current Journal of Neuroscience. Katrin Andreasson and ...

Prostaglandins are natural chemicals in the body with hormone-like qualities. First discovered in semen, prostaglandins were later found in cells throughout the body, as well as in women’s menstrual ...

As we age, it gets harder to recover from a fall, injury or even a tough workout because the body’s muscle-repair system starts to falter. Muscle stem cells (MuSCs), the in-house repair crew, stop ...