Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

Experts explain the science behind chronic pain and how to finally find relief with treatments that target your body and ...

Chemotherapy has long forced patients to choose between fighting their cancer and living with nerve pain that can linger for ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

The hormone estrogen—which female animals typically have more of than males—triggers a molecular cascade in the gut that ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

Scientists have discovered a brain circuit that gives pain its emotional sting, explaining why some hurts linger as suffering. The breakthrough challenges our beliefs about how we process pain and may ...

Researchers at UC Santa Barbara identified a pain pathway in fruit flies that reduces the sensation of pain from heat. The researchers discovered that just a single neuron on each side of the animal’s ...

Pain represents the cardinal symptom of osteoarthritis, yet its intensity, quality, and impact vary dramatically among ...

The American College of Cardiology (ACC) expert decision pathway for chest pain can safely and effectively rule out acute coronary syndromes in most patients, but not for those with known coronary ...

Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...