The neuromuscular junction—where nerves and muscle fibers meet—is an essential synapse for muscle contraction and movement. Improper function of these junctions can lead to the development of ...

MIT scientists have developed a microfluidic chip that mimics the neuromuscular connections that exist at the junction between neurons and the muscles. These junctions are often involved in various ...

As people age, muscles naturally lose mass and strength, a condition known as sarcopenia. The decline can make everyday ...

Neuromuscular diseases are caused by problems in the way muscle cells, motor neurons, and peripheral cells interact. Researchers from the Max Delbrück Center for Molecular Medicine in the Helmholtz ...

After nerve injury, the protein complex mTORC1 takes over an important function in skeletal muscle to maintain the neuromuscular junction, the synapse between the nerve and muscle fiber. Researchers ...

Scanning electron microscopy image of a human neuromuscular junction generated in microfluidic devices. Human induced pluripotent stem cell-derived motor neuron axons fan out and embed themselves into ...

ORLANDO, Fla.--(BUSINESS WIRE)--Hesperos, Inc. has increased its pioneering human-on-a-chip drug testing capabilities by adding a new in vitro, human-human neuromuscular model to its patented ...

The new research could help identify ways to preserve neuromuscular junctions. Muscle-specific kinase (MuSK) is essential to the development of functional neuromuscular junctions, but scientists have ...

New data suggest motor function improves with amifampridine. New phase 2 data for the spinal muscular atrophy (SMA) therapy amifampridine (Ruzurgi) suggests the drug is safe and effective at improving ...

Though motor neurons are the primary victims in amyotrophic lateral sclerosis, it is their waning connections with muscles that ultimately triggers symptoms of the disease. This complex interaction ...