ascopubs.org

Prognostic significance of mutations of nucleophosmin (NPM1) gene and internal tandem duplication of FLT3 gene (FLT3 ITD) in acute myeloid leukemia (AML) with normal karyotype

Genome-wide profiling of DNA copy number abnormalities in adult acute myeloid leukemia (AML) using high density single nucleotide polymorphism array No significant financial relationships to disclose.
ascopubs.org

Association of relapse of FLT3-ITD AML with normal karyotype with internal tandem duplication allelic burden, base-pair insertion length, and NPM1 status.

Activity of the mitochondrial metabolism inhibitor cpi-613 in combination with high dose Ara-C (HDAC) and mitoxantrone in high risk relapsed or refractory acute myeloid leukemia (AML). This is an ASCO ...
Nature

Duplications and copy number variants of 8p23.1 are cytogenetically indistinguishable but distinct at the molecular level

It has been proposed that duplications of 8p23.1 are either euchromatic variants of the 8p23.1 defensin domain with no phenotypic consequences or true duplications associated with developmental delay ...
Medical News Today

What to know about chronic myeloid leukemia and karyotypes

Chronic myeloid leukemia (CML) is a rare blood cancer that develops in the bone marrow. Karyotyping is a genetic technique doctors use to diagnose CML and choose more effective treatments. Karyotyping ...