Figure 1: Atomic models of influenza hemagglutinin at neutral and low pH. Here we studied the interaction of influenza particles with liposome targets to which they fuse at low pH to understand how ...

Though first described several decades ago, single-particle electron cryomicroscopy (cryo-EM) has been a relatively specialized technique, straddling the shadowy area of structural biology between ...

With recent technological advances, the atomic resolution structure of any purified biomolecular complex can, in principle, be determined by single-particle electron cryomicroscopy (cryoEM). In ...

We present the first three-dimensional reconstruction of human fatty acid synthase obtained by electron cryomicroscopy and single-particle image processing. The structure shows that the synthase is ...