Cleavage of cohesins and cyclin-dependent kinase (CDK) inhibition are thought to be sufficient for triggering chromosome segregation. Here we identify an essential requirement for anaphase chromosome ...

We’ve all seen the movie. The sister chromatids hover at the metaphase plate, and then suddenly break apart and race toward the spindle poles. The suddenness of the event is striking: there can be ...

Structural biologists show in a new study that an apparently key step in the process of cell division depends on a unique interaction among specific proteins, including one that is strongly linked to ...

Mitosis and meiosis are both processes by which cells reproduce, but there are distinct differences between the two. While new cells are generated during mitosis, meiosis is a special type of cell ...